Immunogen | MALP-2, TLR6 and TLR2 ligand |
Specificity | MALP-2 was originally isolated from Mycoplasma fermentans. This MALP-2 corresponds to the originally isolated isomer, which expresses potent endotoxin-like activity and approaches in certain experimental systems the toxicity of LPS. For description of the stereochemistry of MALP-2 please refer to M. Morr, et al. Eur. J. Immunol. 32, 3337 (2002). The importance of the stereochemistry of the central carbon atom of the diacylglycerol group has been described in the K.M. Omueti, et al. paper (2005), see below. Formula:C99H167N19O30S |
Details of Functionality | Specific Activity is approx 2x10^8units/mg. One unit is defined as the dilution giving half maximal release of nitric oxide from C3H/HeJ mouse peritoneal exudate cells in the standard assay. |
Application Notes | Source: Synthetic Formula: C99H167N19O30S MW: 2135.2 Use in In- vitro assay and functionalreported in scientific literature (PMID 25466255) | |
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