Additional Information | CHO derived |
Details of Functionality | Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340. The ED50 for this effect is 0.2‑1.2ng/mL.The specific activity of Recombinant Human/Mouse/Rat Activin A is approximately 1 IU/μg, which is calibrated against human ActivinA WHOInternational Standard (NIBSC code: 91/626). |
Source | Chinese Hamster Ovary cell line, CHO-derived Activin A proteinGly311-Ser426 |
Accession # | P08476 |
N-terminal Sequence | Gly311 |
Structure / Form | Disulfide-linked homodimer |
Protein/Peptide Type | Recombinant Proteins |
Gene | INHBA |
Purity | >95%, by SDS-PAGE with silver staining. |
Endotoxin Note | <0.01 eu="" per="" 1="" μg="" of="" the="" protein="" by="" the="" lal="">0.01> |
Theoretical MW | 13 kDa (monomer). Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. | |
SDS-PAGE | 14 kDa, reducing conditions24 kDa, non-reducing conditions | |
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