Details of Functionality | Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Binnerts, M.E. et al. (2004) Biochem. Biophys. Res. Commun. 315(2):272. The ED50 for this effect is typically2.5-15 ng/mL. |
Source | Mouse myeloma cell line, NS0-derived human BMP-4 proteinSer293-Arg408 |
Accession # | Q53XC5 |
N-terminal Sequence | Ser293 |
Structure / Form | Disulfide-linked homodimer |
Protein/Peptide Type | Recombinant Proteins |
Gene | BMP4 |
Purity | >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Endotoxin Note | <0.01 eu="" per="" 1="" μg="" of="" the="" protein="" by="" the="" lal="">0.01> |
Theoretical MW | 13 kDa (monomer). Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. | |
SDS-PAGE | 22-25 kDa, reducing conditions37-41 kDa, non-reducing conditions | |
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